A lot has happened since the days of McDreamy and McSteamy, and even though many of the original cast members are no more - apart from some brief returns in season 17.
There were some doubts over its future but with season 19 confirmed, the show continues Grey's Anatomy.
This is everything we know about Grey's Anatomy season 19, including when it will be released and how to watch it when it is.
You will also find where to binge watch the previous seasons of Grey's Anatomy (all 18 seasons of them).
As for the UK, we normally have to wait a little after the US date before it arrives. Season 18 landed in the US on 30 September 2021.
If season 19 follows a similar pattern, it could arrive in the UK around mid-November, but nothing is confirmed yet.
For those in the US, Grey's Anatomy season 19 will be available on ABC when it arrives. It will also likely stream on Hulu, like season 18 did.
For those in the UK, Grey's Anatomy season 19 will likely come to Sky Witness when it lands. You'll therefore be able to watch them with a Sky or Now subscription.